Myth buster

Creatine does not damage healthy kidneys

No. In healthy adults using ordinary creatine monohydrate, current evidence does not show kidney-function damage. The common trap is reading a creatinine lab change as organ damage.

Short answer

No. In healthy adults using ordinary creatine monohydrate, current evidence does not show kidney-function damage. The common trap is reading a creatinine lab change as organ damage.

A 2025 systematic review found a small serum-creatinine increase without a significant GFR change, and controlled trials using measured GFR, proteinuria, and albuminuria checks did not show matching kidney-function harm in the studied populations. That makes this a lab-interpretation claim, not a proven kidney-damage claim.

Practical takeaway

What to do instead

Keep the reassurance narrow: healthy adult, plain creatine monohydrate, normal kidney context. If you have CKD, unexplained abnormal labs, pregnancy, one kidney, recurrent dehydration risk, or kidney-relevant medications, tell the clinician or lab reviewer about creatine and let them interpret the full kidney picture.

The myth

Creatine damages the kidneys.

At a glance

Best next step